Severe Acute Pancreatitis

• Associated with organ failure and/or local complications such as necrosis
• Clinical manifestations
  • Obesity BMI > 30
  • Hemoconcentration (hematocrit > 44%)
  • Age > 70
• Organ failure^a
  • Shock
  • Pulmonary insufficiency (P_O2 < 60)
  • Renal failure (CR > 2.0 mg%)
  • GI bleeding
• ≥ 3 Ransom criteria (not fully utilizable until 48 h)
• Apache II score > 8 (cumbersome)

^aUsually declares itself shortly after onset.